Description
Technical Parameters
| Name | Fosfomycin calcium |
|---|---|
| Other name | Phosphomycin calcium salt; phosphonomycin calcium salt;(-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid |
|
Biochemical mechanism |
Fosfomycin Calcium is the Ca2+ salt preparation of Fosfomycin, a phosphonic acid epoxide antibiotic. Fosfomycin is described to inhibit cell wall synthesis throμgh inhibition of UDP-N-acetylglucosamine enolpyruvyl transferase, the enzyme responsible for catalysis of the first committed step in peptidoglycan biosynthesis.Broad spectrum antibiotic. Inhibits UDP-N-acetylglucosamine enolpyruval transferase to inhibit bacterial wall synthesis. Orally active. |
| Transport Condition | Normal |
| Usage |
A bacterial wall synthesis inhibitor A bacterial wall synthesis inhibitor |
Names and marks
| IUPAC Name | calcium;[(2R,3S)-3-methyloxiran-2-yl]-dioxido-oxo-位5-phosphane |
|---|---|
| INCHI | InChI=1S/C3H7O4P.Ca/c1-2-3(7-2)8(4,5)6;/h2-3H,1H3,(H2,4,5,6);/q;+2/p-2/t2-,3+;/m0./s1 |
| InChi Key | YMZJBJPWTXJQMR-LJUKVTEVSA-L |
| Canonical SMILES | CC1C(O1)P(=O)([O-])[O-].[Ca+2] |
| Formula |
C3H5O4PCa |
| PubChem CID | 93095 |
|
Molecular Weight |
176.12 |
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